Friday, February 23, 2018

GRCg6: Curation of the chicken reference genome assembly transfers to the GRC



The GRC announces the release of the latest chicken reference genome assembly, GRCg6.


The chicken reference assembly defines a standard upon which other avian whole genome studies are based. Providing the best representation of the chicken genome is essential for facilitating continued progress in understanding and improving human health as this species serves as a model organism similar to mouse, zebrafish and other vertebrates.

The chicken reference genome project began as an international research collaboration coordinated by the McDonnell Genome Institute with past funding from the National Institutes of Health (NIH) and U.S. Department of Agriculture whose shared goals were to determine the sequence of the chicken chromosomes and annotate all possible chicken genes. The initial genome reference was completed and published in Nature in 2004 and has since evolved in quality. The reference experienced a major upgrade in 2016, termed Gallus_gallus-5.0 (GCA_000002315.3), as a result of long read sequencing technology and added transcriptome data. In 2017, responsibility for the management of chicken genome assembly updates transferred to the Genome Reference Consortium (GRC). The generation of additional sequence coverage comprised of long read data, in particular average read lengths of 12kb, as well as improvements to de novo assembly algorithms has resulted in another upgrade, GRCg6, that has now been released for immediate community use. Manual annotation of de novo assembled contigs that have been integrated with finished BAC clones have produced an assembly with superior metrics of quality, such as N50 contig size of 18Mb and much lower gap counts.


Visit the chicken homepage at the GRC website for assembly notifications, report assembly issues or contact us with questions.

The GRCg6 assembly will be available in all major genome browsers, and will be annotated by both the NCBI eukaryotic genome annotation pipeline and Ensembl.

* Photo courtesy of Dr. Jerry Dodgson 

11 comments:


  1. I just wanted to say thank you for sharing a great information and useful. it really necessary and timely for me at this time. I've read a lot of blogs and visit but they made me feel boring. Your article made me feel strange and fascinating it attracted me. I wanted to share this information with my friends on the social network facebook.!

    Swing sets

    ReplyDelete
  2. Very informative and useful historical post. I see you have a lot of other cool stuff available at your website, simply bookmarking it to check in spare time. Thanks and keep the good work up.

    Wooden Swing sets

    ReplyDelete
  3. Very informative and useful historical post. I see you have a lot of other cool stuff available at your website, simply bookmarking it to check in spare time. Thanks and keep the good work up.

    Wooden Swing sets

    ReplyDelete
  4. I really loved reading your blog. It was very well authored and easy to undertand. Unlike additional blogs I have read which are really not tht good. I also found your posts very interesting. In fact after reading, I had to go show it to my friend and he ejoyed it as well!

    Outdoor play

    ReplyDelete
  5. Very informative and useful historical post. I see you have a lot of other cool stuff available at your website, simply bookmarking it to check in spare time. Thanks and keep the good work up.

    Wooden Swing sets

    ReplyDelete
  6. Great post. I was once checking constantly this weblog and I'm impressed! Extremely useful information specially the closing part. I maintain such information much. I was once seeking this specific information for a very long time. Many thanks and best of luck.


    Outdoor play

    ReplyDelete
  7. Great post. I was once checking constantly this weblog and I'm impressed! Extremely useful information specially the closing part. I maintain such information much. I was once seeking this specific information for a very long time. Many thanks and best of luck.


    Outdoor play

    ReplyDelete
  8. Very informative post. Your post really gonna help the people like me who are looking for such terms and info.... I am glad i visited here and learned.


    Swing sets

    ReplyDelete
  9. Great post. I was once checking constantly this weblog and I'm impressed! Extremely useful information specially the closing part. I maintain such information much. I was once seeking this specific information for a very long time. Many thanks and best of luck.


    Outdoor play

    ReplyDelete
  10. I wanted to thank you for this great read!! I definitely enjoying every little bit of it I have you bookmarked to check out new stuff you post.

    Playset Assembly

    ReplyDelete
  11. Wow, what a blog! I mean, you just have so much guts to go ahead and tell it like it is. Youre what blogging needs, an open minded superhero who isnt afraid to tell it like it is. This is definitely something people need to be up on. Good luck in the future, man

    Swing set Installation

    ReplyDelete